Biomed Res Int. 2020;16(2):135-142. Vanderhoof JA, Young RJ. Effect of Lactobacillus on the incidence and severity of acute rotavirus diarrhoea in infants. Am J Gastroenterol 2010;105;1636-41. BMJ 2002;324:1361. 2012;54(5):682-7. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. J Am Coll Nutr 2001;20:149-56. No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Rosenfeldt V, Michaelsen KF, Jakobsen M, et al. Am J Clin Nutr 2001;73;1124S-1130S. View abstract. Wagner RD, Pierson C, Warner T, et al. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. View abstract. A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 2013;132(3):e666-76. 2014;40(2):200-7. Newcomer AD, Park HS, O'Brien PC, McGill DB. Pediatr Int. Uses. View abstract. CMAJ Open. Short bowel syndrome: People with short bowel syndrome might be more likely than other people to develop lactobacillus infections. View abstract. World J Gastroenterol. Kim HJ, Camilleri M, McKinzie S, et al. Lactobacillus acidophilus has been used in alternative medicine as a likely effective aid in treating diarrhea in children with rotavirus. Saxelin M, Chuang NH, Chassy B, et al. This content does not have an Arabic version. Gastroenterology 2020;159(2):467-80. J Antimicrob Chemother 2003;52:308-11. Eat Weight Disord. View abstract. For a bowel condition called ulcerative colitis: A combination probiotic containing 450 billion to 1800 billion bacteria, including Lactobacillus, Bifidobacterium, and Streptococcus (VSL#3), has been used daily in children with moderate-to-severe ulcerative colitis. Bacterial interference for prevention of urinary tract infection: an overview. Gill HS, Rutherfurd KJ. rhamnosus, Lactobacillus crispatus, Lactobacillus delbrueckii, Lactobacillus delbrueckii ssp. J Pediatr Gastroenterol Nutr 1997;24:399-404. View abstract. For preventing diarrhea caused by antibiotics: A specific beverage (Actimel, Danone) containing Lactobacillus casei, Lactobacillus bulgaricus, and Streptococcus thermophilus (Actimel, Danone) 97 mL has been taken twice daily. J Matern Fetal Neonatal Med. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbl DE. Prospective, randomized, open-label trial comparing the safety, efficacy, and tolerability of an acne treatment regimen with and without a probiotic supplement and minocycline in subjects with mild to moderate acne. Clin Infect Dis 1999;28:1159-60. View abstract. Szajewska H, Kotowska M, Mrukowicz JZ, et al. View abstract. Oberhelman RA, Gilman RH, Sheen P, et al. View abstract. Lactobacillus acidophilus is also possibly effective in treating irritable bowel syndrome, bacterial vaginal infection, colic in babies, lung infections in children, skin problems in children who are allergic to milk, and other conditions. 2002;62(2):159-63. Venturi A, Gionchetti P, Rizzello F, et al. Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression. show all 12 brands View abstract. Hegar B, Hutapea EI, Advani N, Vandenplas Y. 2013;32(6):928-34. Appl Environ Microbiol 1997;63:513-8. Ishikawa H, Akedo I, Umesaki Y, et al. 2014;30(3):847-53. A prospective placebo-controlled double-blind study. Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations. Taking L. acidophilus by mouth along with most standard drug therapies helps treat. Therapy of bacterial vaginosis using exogenously-applied Lactobacilli acidophili and a low dose of estriol: a placebo-controlled multicentric clinical trial. Francavilla R, Polimeno L, Demichina A, Maurogiovanni G, Principi B, Scaccianoce G, Ierardi E, Russo F, Riezzo G, Di Leo A, Cavallo L, Francavilla A, Versalovic J. Lactobacillus reuteri strain combination in Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. 2017;9(4):380-385. Lactobacillus is also LIKELY SAFE for women to use inside the vagina. Effect of Lactobacillus sakei supplementation in children with atopic eczema-dermatitis syndrome. View abstract. Appl Environ Microbiol 1996;62:1958-63. Martinelli M, Ummarino D, Giugliano FP, et al. 2019;2019:5364730. Lactobacillus acidophilus preparations (containing sodium carboxymethylcellulose): 2 capsules 24 times daily. The Efficacy of Bifidobacterium longum BORI and Lactobacillus acidophilus AD031 Probiotic Treatment in Infants with Rotavirus Infection. Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection. ATC class: G01AX14. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Marini A, Jaenicke T, Grether-Beck S, Le Floc'h C, Cheniti A, Piccardi N,Krutmann J. Tursi A, Brandimarte G, Giorgetti GM, et al. J Pediatr Gastroenterol Nutr 1997;24:399-404. 2014;30(4):189-94. View abstract. 2012;28(10):1048-51. 2012 18;157(12):878-88. Review. Safety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virus. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-controlled triple-blind study. Review/update the Do not use in patients with weakened immune system. J Pediatr Gastroenterol Nutr 1997;25:516-9. Elimination of vaginal colonization with Escherichia coli by administration of indigenous flora. Nutr J. supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. Int J Food Microbiol 1998;41:195-204. What Is Exocrine Pancreatic Insufficiency? 2020;10(1):1-1. Fujisawa T, Benno Y, Yaeshima T, Mitsuoka T. Taxonomic study of the Lactobacillus acidophilus group, with recognition of Lactobacillus gallinarum sp. Not all possible interactions are listed in this product guide. Chan RCY, Reid G, Irvin RT, et al. Gionchetti P, Rizzello F, Venturi A, et al. Gionchetti P, Rizzello F, Venturi A, et al. Lactobacillus GG in the prevention of antibiotic-associated diarrhea in children. Shimizu M, Hashiguchi M, Shiga T, Tamura HO, Mochizuki M. Meta-analysis: effects of probiotic supplementation on lipid profiles in normal to mildly hypercholesterolemic individuals. Another cool skill of Lactobacillus acidophilus is it produces the enzyme lactase. Pregnant and lactating women should be advised that usage of this drug should only be in situations where the benefits clearly outweigh the risks. 2013;17(2):114-22. Gastroenterology 1996;111:334-44. Cholesterol-lowering efficacy of Lactobacillus plantarum CECT 7527, 7528 and 7529 in hypercholesterolaemic adults Br J Nutr 2013;109(10):1866-72. 2021;147(1):e20200706. To avoid this interaction, take L. acidophilus products at least 2 hours before or after antibiotics. A randomized clinical trial. Experimental and clinical study on the hypolipidemic and antisclerotic effect of Lactobacillus bulgaricus strain GB N 1 (48). Wang YH, Huang Y. Nutritional and therapeutic aspects of lactobacilli. Lactobacillus acidophilus and bulgaricus has been used as a probiotic to aid in digestion, to prevent diarrhea, and to relieve symptoms of irritable bowel syndrome. Postgrad Med J 2002;78:366-7. Can J Microbiol 1988;34:339-43. Probiotics: effects on immunity. Mao Y, Nobaek S, Kasravi B, et al. Wendakoon CN, Thomson AB, Ozimek L. Lack of therapeutic effect of a specially designed yogurt for the eradication of Helicobacter pylori infection. Beausoleil, M., Fortier, N., Guenette, S., L'ecuyer, A., Savoie, M., Franco, M., Lachaine, J., and Weiss, K. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial. Scand J Infect Dis 1990;22:43-7. Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis. Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, Fitzharris P, Purdie G, Crane J. J Pediatr Gastroenterol Nutr 2000;30:54. Pediatrics 2007;119:e124-30. View abstract. Antibiotics. Guandalini S, Pensabene L, Zikri MA, et al. View abstract. Jiang H, Zhang Y, Xu D, Wang Q. Probiotics ameliorates glycemic control of patients with diabetic nephropathy: A randomized clinical study. View abstract. View abstract. Copyright 2023, Selected Revisions November 1, 2007. Friend BA, Shahani KM. View abstract. J Clin Microbiol 1995;33:1433. Pediatr Diabetes 2021;22(7):1014-1022. Kuhbacher T, Ott SJ, Helwig U, et al. View abstract. Scand J Infect Dis 2003;35:365-7. . Parma M, Dindelli M, Caputo L, Redaelli A, Quaranta L, Candiani M. The role of vaginal Lactobacillus Rhamnosus (Normogin) in preventing Bacterial Vaginosis in women with history of recurrences, undergoing surgical menopause: a prospective pilot study. View abstract. Ann Intern Med. Am J Gastroenterol 2002;97:2744-9. View abstract. View abstract. Helicobacter. View abstract. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Darouiche RO, Hull RA. Cochrane Database Syst Rev 2020;6(6):CD012970. A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndrome. View abstract. Cheng B, Zeng X, Liu S, Zou J, Wang Y. Wang L, Guo MJ, Gao Q, Yang JF, Yang L, Pang XL, Jiang XJ. 2015;33:25. Appl Environ Microbiol 1997;63:513-8. For a condition associated with an increased risk for developing allergic reactions (atopic disease): Ten to 20 billion CFU of Lactobacillus GG has been used daily for the first three to six months of life. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. View abstract. 1st ed. View abstract. View abstract. J Allergy Clin Immunol 2007;119:1174-80.. View abstract. 1st ed. View abstract. Sanchez M, Darimont C, Drapeau V, Emady-Azar S, Lepage M, Rezzonico E, View abstract. We comply with the HONcode standard for trustworthy health information. May provide relief to patients with hives, fever blisters, canker sores, and adolescent acne; however, results in these largely self-limiting conditions have been equivocal. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. information and will only use or disclose that information as set forth in our notice of Pediatr Infect Dis J 1997;16:1103-7. View abstract. O'Sullivan MA, O'Morain CA. Lactobacillus acidophilus (L. acidophilus) is a type of probiotic ("good" bacteria) found in the human gut, mouth, and vagina, and also in certain foods. PLoS One 2015;10(10):e0139795. 2013;105(8):445-53. Review. Lower doses might not be as effective. Roberfroid MB. View abstract. Effect of Lactobacillus on the incidence and severity of acute rotavirus diarrhoea in infants. Lactobacillus is also taken by mouth for infection with Helicobacter pylori, the type of bacteria that causes ulcers, and also for other types of infections including urinary tract infections (UTIs), vaginal yeast infections, to prevent the common cold and flu, to prevent ear infections in children, and to prevent respiratory infections in children attending daycare centers and in children with cystic fibrosis. Ask a doctor before using this product if you are pregnant or breast-feeding. Written by ASHP. J Clin Microbiol 1998;36:1781-3. Infect Immun 1985;47:84-9. Powder or liquid forms may also be available. Br J Nutr 2012;107(1):1-6. View abstract. View abstract. You may opt-out of email communications at any time by clicking on The Role of Probiotics in the Treatment of Dysentery: a Randomized Double-Blind Clinical Trial. View abstract. Savino F, Cordisco L, Tarasco V, et al. Med Sci Monit 2004;10:PI126-31. World J Gastroenterol 2012;18(43):6250-4. Although not all side effects are known, lactobacillus acidophilus is thought to be likely safe when taken for a short period of time. Common side effects may include: gas. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. View abstract. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. View abstract. Koning CJ, Jonkers DM, Stobberingh EE, et al. Also, 37 billion CFU of Lactobacillus GG has been used daily, 6 days weekly, for 15 months in children 6 to 24 months-old. Prebiotics and probiotics: are they functional foods? View abstract. Oral Microbiol Immunol 2006;21:129-31. Gaon D, Garmendia C, Murrielo NO, et al. Meta-analysis of the efficacy and safety of Lactobacillus-containing and Bifidobacterium-containing probiotic compound preparation in Helicobacter pylori eradication therapy. 2013;19(12):2584-92. information highlighted below and resubmit the form. Effect of the oral administration of Lactobacillus brevis subsp. 2019;13(1):175-182. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. View abstract. View abstract. Sci Rep. 2020;10(1):4183. Acta Paediatr 2010;99:1135-8. Improvement of lactose digestion by humans following ingestion of unfermented acidophilus milk: influence of bile sensitivity, lactose transport, and acid tolerance of Lactobacillus acidophilus. Allen SJ, Wareham K, Wang D, Bradley C, Sewell B, Hutchings H, Harris W, Dhar A, Brown H, Foden A, Gravenor MB, Mack D, Phillips CJ. Am J Gastroenterol 2005;100:1539-46. Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk. The effect of Lactobacillus GG on the initiation and promotion of DMH-induced intestinal tumors in the rat. Nutr Res 2002;22:393-403. View abstract. Casas IA, Dobrogosz WJ. Reid G, Cook RL, Bruce AW. Treatment of irritable bowel syndrome with Lacteol Fort: a randomized, double-blind, cross-over trial.